"And you ... hath he reconciled in the body of his flesh through death, to present you holy and unblameable and unreprovable" (Colossians 1:21-22).
For the moral unlikeness between man and God the Bible has a word, alienation, and the Holy Spirit presents a frightful picture of this alienation as it works itself out in human character.
Fallen human nature is precisely opposite to the nature of God as revealed in Jesus Christ. Because there is no moral likeness there is no communion, hence the sense of physical distance, the feeling that God is far away in space.
The new birth makes us partakers of the divine nature. There the work of undoing the dissimilarity between us and God begins. From there it progresses by the sanctifying operation of the Holy Spirit till God is satisfied.
The only remedy for human nature is to destroy it and receive instead the divine nature. God does not improve man. He crucifies the natural life with Christ and creates the new man in Christ Jesus.
~A. W. Tozer~